HLA-C*04:01 Affects HLA Class I Heterozygosity and Predicted Affinity to SARS-CoV-2 Peptides, and in Combination With Age and Sex of Armenian Patients Contributes to COVID-19 Severity
Anahit Hovhannisyan; Vergine Madelian; Sevak Avagyan; Mihran Nazaretyan; Armine Hyussyan; Alina Sirunyan; Rubina Arakelyan; Zorayr Manukyan; Levon Yepiskoposyan; Karine R. Mayilyan, and F. Jordan · 2022
Catalogue summary
Using data from 299 Armenian patients, this immunology study tests associations between particular HLA variants, demographic factors, and differing levels of COVID-19 severity.
Why this matters
It contributes population-specific biomedical evidence from Armenians and illustrates why genetic associations should be evaluated within well-defined cohorts rather than generalized indiscriminately.
Citation
Anahit Hovhannisyan; Vergine Madelian; Sevak Avagyan; Mihran Nazaretyan; Armine Hyussyan; Alina Sirunyan; Rubina Arakelyan; Zorayr Manukyan; Levon Yepiskoposyan; Karine R. Mayilyan, and F. Jordan 2022. HLA-C*04:01 Affects HLA Class I Heterozygosity and Predicted Affinity to SARS-CoV-2 Peptides, and in Combination With Age and Sex of Armenian Patients Contributes to COVID-19 Severity. Frontiers in Immunology. https://doi.org/10.3389/fimmu.2022.769900
Related in the repository
Publication details and source links are provided for discovery. Consult the linked publisher or repository record as the source of authority.